Ever heard of a human turning into stone? A rare genetic disorder called fibrodysplasia ossificans progressiva (FOP) causes hardening of certain joints in the body as muscle tissue and tendons are replaced by bone resulting in complete loss of mobility of that joint.
This condition affects 800 million people worldwide. Small bony lumps may appear in different parts, especially neck and shoulders. Signs are visible from birth (shorter bog toes) but often physicians are not able to diagnose it very early.
A case of twin sisters (now age 26) from Ireland gradually losing body movement (turning into stone) has brought this disease condition to the forefront. Until recently there was no specific treatment available but a clinical trial using a new drug is underway and medical fraternity as well as patients across the globe eagerly await a positive response.
References:
https://rarediseases.org/rare-diseases/fibrodysplasia-ossificans-progressiva/